Springhouse, PA: Springhouse Corp., 1999. Antibiotics (Quinolone antibiotics) interacts with YERBA MATE. Dreher HM. Involvement of human CYP1A isoenzymes in the metabolism and drug interactions of riluzole in vitro. Pharmacogenetics 1996;6(3):213-222. Joeres R, Klinker H, Heusler H, et al. Med J Aust 2001;174:520-1. View abstract. Clin Pharmacol Ther 1989;45:234-40. Information from this source is evidence-based and objective, and without commercial influence. ROTH, J. L. Clinical evaluation of the caffeine gastric analysis in duodenal ulcer patients. Known and hidden sources of caffeine in drug, food, and natural products. Chaves G, Britez N, Oviedo G, et al. Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes. 1998;36(1):112-114. N Engl J Med 2000;343:1833-8. Pharmacol Rep. 2009;61(6):1216-1220. Mays, D. C., Camisa, C., Cheney, P., Pacula, C. M., Nawoot, S., and Gerber, N. Methoxsalen is a potent inhibitor of the metabolism of caffeine in humans. Massive catecholamine release from caffeine poisoning. Cardiology in the Elderly 1994;2:499-503. Avoid taking stimulant drugs along with mate. The yerba mate intake has a neutral effect on bone: a case-control study in postmenopausal women. Bell DG, Jacobs I, Ellerington K. Effect of caffeine and ephedrine ingestion on anaerobic exercise performance. May Protect Against Infections. View abstract. Phytother Res. Sanderink GJ, Bournique B, Stevens J, et al. Anesthesiology 1972;36:37-41. Br J Clin Pharmacol 2000;49:59-63. Impairment of caffeine clearance by chronic use of low-dose oestrogen-containing oral contraceptives. Mattila ME, Mattila MJ, Nuotto E. Caffeine moderately antagonizes the effects of triazolam and zopiclone on the psychomotor performance of healthy subjects. Matsumoto, R. L., Bastos, D. H., Mendonca, S., Nunes, V. S., Bartchewsky, W., Ribeiro, M. L., and de Oliveira, Carvalho P. Effects of mate tea (Ilex paraguariensis) ingestion on mRNA expression of antioxidant enzymes, lipid peroxidation, and total antioxidant status in healthy young women. View abstract. Caffeine, urinary calcium, calcium metabolism and bone. Yerba mate is a type of tea drunk extensively in South America. A pharmacodynamic interaction between caffeine and phenylpropanolamine. View abstract. Some people take yerba mate by mouth to relieve mental and physical tiredness (fatigue), as well as chronic fatigue syndrome (CFS). Chou T. Wake up and smell the coffee. Juliano LM, Griffiths RR. The body breaks down the caffeine in mate to get rid of it. J Am Coll Nutr. Meyer, K. and Ball, P. Psychological and Cardiovascular Effects of Guarana and Yerba Mate: A Comparison with Coffee. BOX 29201 J Am Heart Assoc. The body breaks down caffeine to get rid of it. Pharmacol.Rep. Pittler, M. H. and Ernst, E. Dietary supplements for body-weight reduction: a systematic review. Martin, I., Lopez-Vilchez, M. A., Mur, A., Garcia-Algar, O., Rossi, S., Marchei, E., and Pichini, S. Neonatal withdrawal syndrome after chronic maternal drinking of mate. Diet and risk of atrial fibrillation - epidemiologic and clinical evidence -. Stanek EJ, Melko GP, Charland SL. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Stamford, CT: Appleton & Lange, 1999. McEvoy GK, ed. This supplement has been around for a while and has a decent reputation and widespread name recognition. J Agric.Food Chem. The caffeine in mate can stimulate the body. View abstract. Caffeine impairs glucose metabolism in type 2 diabetes. Holmgren P, Norden-Pettersson L, Ahlner J. Caffeine fatalities--four case reports. The Rancho Bernardo Study. Taking mate along with clozapine (Clozaril) can increase the effects and side effects of clozapine (Clozaril). Stimulant drugs such as nicotine speed up the nervous system. Diabetes. Sinclair CJ, Geiger JD. Mattila MJ, Nuotto E. Caffeine and theophylline counteract diazepam effects in man. 12-15-2011;19(1):88-97. Estroven ® Menopause Relief + Energy is designed with these symptoms in mind. View abstract. The effect of mate extract on body weight and fat reduction in obese women: a randomized placebo-controlled clinical trial. Infante S, Baeza ML, Calvo M, et al. Indian J.Exp.Biol. Some antibiotics might decrease how quickly the body breaks down caffeine. Effect of chocolate and mate tea on the lipid profile of individuals with HIV/AIDS on antiretroviral therapy: a clinical trial. Aqel RA, Zoghbi GJ, Trimm JR, et al. J Am Heart Assoc. 1997;25(11):1298-1303. Uncontrolled Blood Sugar: How Dangerous Is It? Phenylpropanolamine interacts with YERBA MATE. J Neurol Neurosurg Psychiatr 2000;68:112-3. Dissociation of augmented physiological, hormonal and cognitive responses to hypoglycaemia with sustained caffeine use. However, some studies indicate that people who drink large amounts of yerba mate over prolonged periods may be at increased risk of some types of cancer, such as cancer of the mouth, esophagus and lungs. Pharmacotherapy: A pathophysiologic approach. Am J Hosp Pharm 1979;36:754-7. Massey LK. 2017 Nov-Dec;43-44:61-68. J Nutr 2005;135:1120-3. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. Underwood DA. American Academy of Pediatrics. The leaves are used to make medicine. Holmgren P, Norden-Pettersson L, Ahlner J. Caffeine fatalities--four case reports. Decreasing the breakdown of caffeine can cause jitteriness, headache, fast heartbeat, and other side effects. Like tea from the tea plant, there is some evidence that it could be a health promoting drink. A synopsis of Laboratory Medicine. Washington, DC: National Academy Press, 2001. Indian J.Exp.Biol. Behavioral and physiological effects of xanthines in nonhuman primates. Acheson KJ, Gremaud G, Meirim I, et al. 2001;75(2-3):291-294. Arch Intern Med 1995;155:2245-8. For Dieter, Nearly the Ultimate Loss. Avisar R, Avisar E, Weinberger D. Effect of coffee consumption on intraocular pressure. Br J Clin Pharmacol 1981;12:155-9. Available at: http://books.nap.edu/books/0309082587/html/index.html. Fernandes O, Sabharwal M, Smiley T, et al. N Engl J Med 1999;341:1639-44. Proposed rule: dietary supplements containing ephedrine alkaloids. Clin Pharmacol Ther 1991;50:363-71. Gasior, M., Borowicz, K., Buszewicz, G., Kleinrok, Z., and Czuczwar, S. J. Anticonvulsant activity of phenobarbital and valproate against maximal electroshock in mice during chronic treatment with caffeine and caffeine discontinuation. Crit Care Resusc. Estroven is an over-the-counter supplement aimed at treating symptoms of menopause. View abstract. Pharmacol Rep. 2006;58(5):652-659. View abstract. It is made from the leaves of a plant in the Holly family, and is caffeine rich. Martinet, A., Hostettmann, K., and Schutz, Y. Thermogenic effects of commercially available plant preparations aimed at treating human obesity.

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